Do a physical exam, which will likely include an exam of your penis, testicles and rectum. PLUS, the latest news on medical advances and breakthroughs from Harvard Medical School experts. Best, Dr. Emer. WTF. Many men with retrograde ejaculation are able to get their partners pregnant once they seek treatment. Even Viagra wouldnt get me hard. Archivio Istituzionale della Ricerca Unimi, NCI CPTC Antibody Characterization Program, Agis-Balboa R.C., Guidotti A., Pinna G. 5alpha-reductase type I expression is downregulated in the prefrontal cortex/Brodmann's area 9 (BA9) of depressed patients. Btw, something weird happening on propeciahelp forums. Don't listen to bad doctors who tell you its all in your head. Do they benefit from people who have pfs so their foundation can continue and ask for more donations? FOIA For what it's worth, here's a couple similar success stories involving numbness, but from PSSD instead of PFS: Testosterone along with initial estrogen management , completely cured my pssd, everything from numbness, to hard on quality , no morning wood, to actually having sexual desires again. Mesterolone (Proviron) is one of the best compounds that can be used for treating Post Finasteride Syndrome in my opinion. I took a step back and said forget about PFS with these blood tests and these symptoms, whats the normal course of action? Is Post Finasteride Syndrome Real? After I got PFS my libido died, I stopped liking women, my brain wouldn't work, and my personality changed to a 90 old man. Eliminate Trigger Foods. Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients. -, Baas W.R., Butcher M.J., Lwin A., Holland B., Herberts M., Clemons J., Delfino K., Althof S., Kohler T.S., McVary K.T. There was this guy on propecia help called JustQuitDut who was a complete psycho, who thought that taking TRT with estrogen blockers would somehow solve it. 2022 Oct;11(10):1452-1457. doi: 10.21037/tau-22-92. Palliative care frightens some people: Heres how it helps, Parents don't always realize that their teen is suicidal. Like I said, almost starting to believe they want people to keep having pfs so they can benefit in some form or another. The common denominator in how I feel is Tribulus, period, end of sentence. ._2FKpII1jz0h6xCAw1kQAvS{background-color:#fff;box-shadow:0 0 0 1px rgba(0,0,0,.1),0 2px 3px 0 rgba(0,0,0,.2);transition:left .15s linear;border-radius:57%;width:57%}._2FKpII1jz0h6xCAw1kQAvS:after{content:"";padding-top:100%;display:block}._2e2g485kpErHhJQUiyvvC2{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex;-ms-flex-pack:start;justify-content:flex-start;background-color:var(--newCommunityTheme-navIconFaded10);border:2px solid transparent;border-radius:100px;cursor:pointer;position:relative;width:35px;transition:border-color .15s linear,background-color .15s linear}._2e2g485kpErHhJQUiyvvC2._3kUvbpMbR21zJBboDdBH7D{background-color:var(--newRedditTheme-navIconFaded10)}._2e2g485kpErHhJQUiyvvC2._3kUvbpMbR21zJBboDdBH7D._1L5kUnhRYhUJ4TkMbOTKkI{background-color:var(--newRedditTheme-active)}._2e2g485kpErHhJQUiyvvC2._3kUvbpMbR21zJBboDdBH7D._1L5kUnhRYhUJ4TkMbOTKkI._3clF3xRMqSWmoBQpXv8U5z{background-color:var(--newRedditTheme-buttonAlpha10)}._2e2g485kpErHhJQUiyvvC2._1asGWL2_XadHoBuUlNArOq{border-width:2.25px;height:24px;width:37.5px}._2e2g485kpErHhJQUiyvvC2._1asGWL2_XadHoBuUlNArOq ._2FKpII1jz0h6xCAw1kQAvS{height:19.5px;width:19.5px}._2e2g485kpErHhJQUiyvvC2._1hku5xiXsbqzLmszstPyR3{border-width:3px;height:32px;width:50px}._2e2g485kpErHhJQUiyvvC2._1hku5xiXsbqzLmszstPyR3 ._2FKpII1jz0h6xCAw1kQAvS{height:26px;width:26px}._2e2g485kpErHhJQUiyvvC2._10hZCcuqkss2sf5UbBMCSD{border-width:3.75px;height:40px;width:62.5px}._2e2g485kpErHhJQUiyvvC2._10hZCcuqkss2sf5UbBMCSD ._2FKpII1jz0h6xCAw1kQAvS{height:32.5px;width:32.5px}._2e2g485kpErHhJQUiyvvC2._1fCdbQCDv6tiX242k80-LO{border-width:4.5px;height:48px;width:75px}._2e2g485kpErHhJQUiyvvC2._1fCdbQCDv6tiX242k80-LO ._2FKpII1jz0h6xCAw1kQAvS{height:39px;width:39px}._2e2g485kpErHhJQUiyvvC2._2Jp5Pv4tgpAsTcnUzTsXgO{border-width:5.25px;height:56px;width:87.5px}._2e2g485kpErHhJQUiyvvC2._2Jp5Pv4tgpAsTcnUzTsXgO ._2FKpII1jz0h6xCAw1kQAvS{height:45.5px;width:45.5px}._2e2g485kpErHhJQUiyvvC2._1L5kUnhRYhUJ4TkMbOTKkI{-ms-flex-pack:end;justify-content:flex-end;background-color:var(--newCommunityTheme-active)}._2e2g485kpErHhJQUiyvvC2._3clF3xRMqSWmoBQpXv8U5z{cursor:default}._2e2g485kpErHhJQUiyvvC2._3clF3xRMqSWmoBQpXv8U5z ._2FKpII1jz0h6xCAw1kQAvS{box-shadow:none}._2e2g485kpErHhJQUiyvvC2._1L5kUnhRYhUJ4TkMbOTKkI._3clF3xRMqSWmoBQpXv8U5z{background-color:var(--newCommunityTheme-buttonAlpha10)} For each day that goes by, I get a day of surplus inventory. I took a large amount of DHT (proviron) for 7 weeks at 200 mg per day to reduce receptor sensitivity to DHT. I took 2 capsules before my daily workout at around 6pm and another 4 capsules 20 minutes before bedtime. Am I at risk of complications from this condition? .s5ap8yh1b4ZfwxvHizW3f{color:var(--newCommunityTheme-metaText);padding-top:5px}.s5ap8yh1b4ZfwxvHizW3f._19JhaP1slDQqu2XgT3vVS0{color:#ea0027} Yeah, that guy's comment history is really puzzling: When i dared visit PFS forums, the most miserable users there were still in a better state than me. Bookshelf (photo). The results have been amazing and far too great to chalk it up to just being a placebo. These include: Prostate pain Persistent fatigue, exhaustion Stomach pains and digestive problems Constipation Blurry vision Propecia is the Biggest Regret of my Life Taking Propecia is the biggest regret of my life, PK said. Hello, some finasteride users have reported the reversal of post-finasteride syndrome using HCG as therapy. This after having PFS constantly for 11 years. If you have retrograde ejaculation, you'll likely need treatment to get your female partner pregnant. This site complies with the HONcode standard for trustworthy health information: verify here. Traish AM, Melcangi RC, Bortolato M, Garcia-Segura LM, Zitzmann M. Rev Endocr Metab Disord. Day 1 I felt no difference. On PFS forums, peoples dicks got 1 inch bigger when erect, here and there, they sometimes felt sexual attraction towards women. After a few days I starting liking women again and became sexually from frustrated. A review of the FAERS data on 5-alpha reductase inhibitors: implications for postfinasteride syndrome. Press J to jump to the feed. I took intramuscular injections of HCG every 3 a 5 days 1500 to 3000 ui by injections for 1 months only, and after that some Clomid for 10 days 2 pills by day It helped relaunch the natural testorene levels so my libido increased again i am now totally satisfied with my health :slight_smile: https://forum.propeciahelp.com/t/i-believe-i-have-been-cured-by-accident/4054, Yes After nearly 4 years of suffering, I have finally & fully recovered from Post Finasteride Syndrome, All my symptoms have subsided and improved with this method which takes a while but I am fully functional. After a bit over a week I decreased the dose to 10mg before bedtime and none in the afternoon. doi: 10.1177/0960327119842195. 2015;12:401. Urologic Clinics of North America. This report will provide you with the information you need to understand the current controversies, avoid common pitfalls, and work with your doctor to make informed choices about your prostate health. Hcg I did 3000iu the first day then 250iu every other day for the four weeks. You are spreading nonsense, people have been trying that crap for years to no effect. -. Indeed, some national agencies (e.g., Swedish Medical Products Agency, the Medicines and Healthcare Products Regulatory Agency of UK and the U.S. Food and Drug Administration) required to include multiple persistent side effects within the finasteride labels. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology. In some people with PFS, DHT might be normal, but testosterone and cortisol low and estrogen and prolactin high. Very controversial topic in this forum. Yeah the joe_kool guy or whatever his name is had really good luck with TRT, he is honestly the reason I went down this road. Preparing a list of questions before your appointment can help you make the most of your time together. Public Health. Is my condition likely temporary or chronic? Do you have diabetes or any other chronic health problems? Contemporary management of disorders of male orgasm and ejaculation. Can sperm be retrieved from my bladder and used for fertility treatment? For details, see text., Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. Do you and your partner want to have a baby? I am not aware or scientific evidence that back this up at this time. Therefore, results here discussed indicate that PFS is an emerging clinical problem that needs to be further elucidated. two months back to life after being dead for six years. 2015;104:107. Ejaculation and orgasm disorders. What medications or herbal remedies do you take? Urology. I had a case of PFS that was a severe as it gets. Sometimes, more-advanced assisted reproductive techniques are needed. All of that changed in three days. Q. I have heard that finasteride, which I take for my prostate problem, can cause permanent impotence. Effect of 5-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials. Oh, and to not need to play with and shake the life out of my penis to wake it up. I am 100% reversed Keep in mind if I miss a dose or stop my protocol Pfs comes back full force. The presence of side effects during pharmacological treatment is unfortunately a quite common problem. Samplaski MK, et al. In such cases, treatment depends on the underlying cause. Ohl DA, et al. Other: Issues retaining and producing muscle, rectal muscle pain, spike in lower-abdomen fat, also has anyone noticed a rapid increase in earwax production? Note that prior to this protocol I tried injectable Test enanthate, Masteron, proviron and hcg which made my condition even worse. With prostate cancer deaths overtaking that of breast cancer, it is important to know the side effects of finasteride. I'll never be without this stuff again. That's one of the mildest forms of PFS you can experience. https://old.reddit.com/r/PostFinSyndrome/comments/ogcsjc/i_recovered_from_pfs_it_is_possible/. Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects. Next to no sensitivity in my genitals. PDF | Finasteride was patented in 1984 and approved for medical use in 1992. I dont really understand why theyre like that. Do you have cloudy urine after an orgasm? I think it took 6 months before i felt ready to meet a girl again. The management of retrograde ejaculation: A systematic review and update. WebI cannot say enough about this. How much worse can it get then being a lifeless piece of flesh that hasnt been erect or had any kind of sensation in months and months? I did the first day 300 mg clomid, then 100mg for the first two weeks, 50mg for the third week, and none for the forth week. J Sex Med. ._1QwShihKKlyRXyQSlqYaWW{height:16px;width:16px;vertical-align:bottom}._2X6EB3ZhEeXCh1eIVA64XM{margin-left:3px}._1jNPl3YUk6zbpLWdjaJT1r{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;padding:0 4px}._1jNPl3YUk6zbpLWdjaJT1r._39BEcWjOlYi1QGcJil6-yl{padding:0}._2hSecp_zkPm_s5ddV2htoj{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;display:inline-block;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;margin-left:0;padding:0 4px}._2hSecp_zkPm_s5ddV2htoj._39BEcWjOlYi1QGcJil6-yl{padding:0}._1wzhGvvafQFOWAyA157okr{font-size:12px;font-weight:500;line-height:16px;border-radius:2px;margin-right:5px;overflow:hidden;text-overflow:ellipsis;vertical-align:text-bottom;white-space:pre;word-break:normal;box-sizing:border-box;line-height:14px;padding:0 4px}._3BPVpMSn5b1vb1yTQuqCRH,._1wzhGvvafQFOWAyA157okr{display:inline-block;height:16px}._3BPVpMSn5b1vb1yTQuqCRH{background-color:var(--newRedditTheme-body);border-radius:50%;margin-left:5px;text-align:center;width:16px}._2cvySYWkqJfynvXFOpNc5L{height:10px;width:10px}.aJrgrewN9C8x1Fusdx4hh{padding:2px 8px}._1wj6zoMi6hRP5YhJ8nXWXE{font-size:14px;padding:7px 12px}._2VqfzH0dZ9dIl3XWNxs42y{border-radius:20px}._2VqfzH0dZ9dIl3XWNxs42y:hover{opacity:.85}._2VqfzH0dZ9dIl3XWNxs42y:active{transform:scale(.95)} If your doctor suspects your dry orgasm is something other than retrograde ejaculation, you might need further tests or a referral to a specialist to find the cause. i am so desperate.. i am a female.. i need my hair back.. but o reallu cannot undergoo all this syntomps ( i gained 20 kg on fina and dutasterde.. no muscle stranght anymore.. no way to lose weight.. i really can' t tell a lot about mental and neurological condition.. but II am so depressed too.. but probably because I am bald and fat there must be a way to take fina without sides.. there must be a way..). more https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal What websites do you recommend visiting? Liu L, Zhao S, Li F, Li E, Kang R, Luo L, Luo J, Wan S, Zhao Z. J Sex Med. Pharmaceuticals (Basel). Will my partner and I likely need to use assisted reproductive technology, such as intrauterine insemination, to achieve pregnancy? Stopping finasteride treatment can cause post-finasteride syndrome. This may result in side effects such as memory problems or sexual dysfunction (problems that affect the desire for or ability to have sex). Post-finasteride syndrome wasnt reported in clinical studies, but it has been reported since the drug was approved. Epub 2016 Jul 27. Essentially I took testosterone exogenously And I took hcg afterwards, https://old.reddit.com/r/PSSD/comments/7lfc1e/how_i_fixed_my_pssd/. Biomolecules. I dunno, I dont get it. Finasteride blocks the metabolism of testosterone. Diagnosing and Reversing It", Is Post Finasteride Syndrome Real? This procedure is usually done at the doctor's office. No active 34 year old man should have to be having ED discussions with his physician. Wonder if this would work for me? Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. Instead of having a discussion, nope banned. I haven't introduced any other supplements or medications. Proviron saved my life. If your doctor thinks drugs you are taking might be affecting your ability to ejaculate normally, he or she might have you stop taking them for a period of time. The only thing that makes sense is to push your androgen receptors and epigenetics the opposite way fin did. The steroidogenic inhibitor finasteride reverses pramipexole-induced alterations in probability discounting. Finasteride blocks the metabolism of testosterone. Health Alerts from Harvard Medical School. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Examine your urine for the presence of semen after you have an orgasm. However, the side effects of a medication usually go away when you stop taking it. /*# sourceMappingURL=https://www.redditstatic.com/desktop2x/chunkCSS/IdCard.ea0ac1df4e6491a16d39_.css.map*/._2JU2WQDzn5pAlpxqChbxr7{height:16px;margin-right:8px;width:16px}._3E45je-29yDjfFqFcLCXyH{margin-top:16px}._13YtS_rCnVZG1ns2xaCalg{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;display:-ms-flexbox;display:flex}._1m5fPZN4q3vKVg9SgU43u2{margin-top:12px}._17A-IdW3j1_fI_pN-8tMV-{display:inline-block;margin-bottom:8px;margin-right:5px}._5MIPBF8A9vXwwXFumpGqY{border-radius:20px;font-size:12px;font-weight:500;letter-spacing:0;line-height:16px;padding:3px 10px;text-transform:none}._5MIPBF8A9vXwwXFumpGqY:focus{outline:unset} Don't miss your FREE gift. Ive personally recovered from pfs but what worked for me may not work for you as each of our bodies react differently to this condition depending on individuals factors. ._1sDtEhccxFpHDn2RUhxmSq{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;display:-ms-flexbox;display:flex;-ms-flex-flow:row nowrap;flex-flow:row nowrap}._1d4NeAxWOiy0JPz7aXRI64{color:var(--newCommunityTheme-metaText)}.icon._3tMM22A0evCEmrIk-8z4zO{margin:-2px 8px 0 0} But on day 3, I felt like my old self. Day 2 I noticed a bit more energy, but credited that to having a good night's sleep (did I mention this stuff helps you sleep better, too?) Since it only comes in 5 and 1 mg pills, there isnt much of a choice. Just bombarding their bodies with strong androgens. I felt fine while taking it but it gave me gyno so I stopped. Their attitude is 100% there is no cure, it wont get better, nothing works, anything that does work doesnt work long term, and thats just how it is. Fertility and Sterility. When dosed properly, it can bring DHT within normal ranges very effectively. 2011 Mar;8(3):872-84. doi: 10.1111/j.1743-6109.2010.02157.x. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). Midodrine, a medicine that constricts blood vessels, Chlorpheniramine and brompheniramine, antihistamines that help relieve allergies, Ephedrine, pseudoephedrine and phenylephrine, medicines that help relieve symptoms of the common cold. Advertising revenue supports our not-for-profit mission. sharing sensitive information, make sure youre on a federal 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). That is 250IU, not a typo so youll mix your 5000iu HCG with 5CC water and take 1/4 CC intramuscular three times a week using an insulin needle Have you heard about it? Some people had to use anabolic steroids because herbs weren't strong enough. Accessed Sept. 15, 2016. Best, Dr. Emer. For details, see text. .c_dVyWK3BXRxSN3ULLJ_t{border-radius:4px 4px 0 0;height:34px;left:0;position:absolute;right:0;top:0}._1OQL3FCA9BfgI57ghHHgV3{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex;-ms-flex-pack:start;justify-content:flex-start;margin-top:32px}._1OQL3FCA9BfgI57ghHHgV3 ._33jgwegeMTJ-FJaaHMeOjV{border-radius:9001px;height:32px;width:32px}._1OQL3FCA9BfgI57ghHHgV3 ._1wQQNkVR4qNpQCzA19X4B6{height:16px;margin-left:8px;width:200px}._39IvqNe6cqNVXcMFxFWFxx{display:-ms-flexbox;display:flex;margin:12px 0}._39IvqNe6cqNVXcMFxFWFxx ._29TSdL_ZMpyzfQ_bfdcBSc{-ms-flex:1;flex:1}._39IvqNe6cqNVXcMFxFWFxx .JEV9fXVlt_7DgH-zLepBH{height:18px;width:50px}._39IvqNe6cqNVXcMFxFWFxx ._3YCOmnWpGeRBW_Psd5WMPR{height:12px;margin-top:4px;width:60px}._2iO5zt81CSiYhWRF9WylyN{height:18px;margin-bottom:4px}._2iO5zt81CSiYhWRF9WylyN._2E9u5XvlGwlpnzki78vasG{width:230px}._2iO5zt81CSiYhWRF9WylyN.fDElwzn43eJToKzSCkejE{width:100%}._2iO5zt81CSiYhWRF9WylyN._2kNB7LAYYqYdyS85f8pqfi{width:250px}._2iO5zt81CSiYhWRF9WylyN._1XmngqAPKZO_1lDBwcQrR7{width:120px}._3XbVvl-zJDbcDeEdSgxV4_{border-radius:4px;height:32px;margin-top:16px;width:100%}._2hgXdc8jVQaXYAXvnqEyED{animation:_3XkHjK4wMgxtjzC1TvoXrb 1.5s ease infinite;background:linear-gradient(90deg,var(--newCommunityTheme-field),var(--newCommunityTheme-inactive),var(--newCommunityTheme-field));background-size:200%}._1KWSZXqSM_BLhBzkPyJFGR{background-color:var(--newCommunityTheme-widgetColors-sidebarWidgetBackgroundColor);border-radius:4px;padding:12px;position:relative;width:auto}
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